Integrative Therapeutics | K-PAX MitoNutrient Activator | 60 Tablets
K-PAX MitoNutrient Activator | 60 Tablets:
K-PAX MitoNutrient Activator is designed to be taken in combination with the K-PAX MitoNutrients formula, for patient populations that require additional energy support. This activator supplement contains a proprietary mitochondrial support combination, PLUS low-dose, B-complex vitamins, tyrosine and taurine.
Multi-Nutrient Nutritional Supplement for Mitochondrial Health:
All cells, with the exception of red blood cells, contain mitochondria, organelles that produce adenosine triphosphate (ATP), the cellular "energy currency", from adenosine diphosphate (ADP). In addition, mitochondria are involved in many other processes within the body such as cell signaling and regulation of cellular metabolism. Mitochondrial energy metabolism is a critical part of cellular health and function, and influences overall health.
Optimal mitochondrial function depends on:
Quenching of free radicals produced during normal electron transport chain (ETC) activity
Integrity of mitochondrial cell membranes
The transport of critical metabolites, such as fatty acids, into the mitochondria
The Added Support of the "Activator":
K-PAX MitoNutrient Activator is designed to be taken in combination with K-PAX MitoNutrients in those patient populations that require additional energy support. A differentiating feature is the addition of caffeine along with B-complex vitamins, tyrosine and taurine. Developed by Dr. Kaiser, through diligent trial and error, he found that some patients did not experience the expected results when taking the mitochondrial nutrients alone, but responded well with the addition of low-dose caffeine. The low-dose caffeine in K-PAX MitoNutrient Activator is designed to act as a catalyst to the basic mitochondrial support nutrient formula. Preclinical and mechanistic studies support the inclusion of caffeine, notably because caffeine increases hippocampal mitochondrial respiratory rates and may induce mitochondrial biogenesis.1, 2
Individuals requiring additional support may add 1-2 tablets per day of K-PAX MitoNutrient Activator in addition to K-PAX MitoNutrients. Individuals may take this combination until the desired effects are seen, at which time the K-PAX MitoNutrient Activator may be re-evaluated.
K-PAX MitoNutrients and K-PAX MitoNutrient Activator were formulated by Jon D. Kaiser, MD who has 25 years of experience exploring in immune and mitochondrial health. K-PAX MitoNutrients and K-PAX MitoNutrient Activator are the original formulas which feature a unique micronutrient combination to support mitochondrial health and cellular energy support. K-PAX MitoNutrients is part of an approach that investigated the impact on occasional fatigue and mental alertness.3
1- Dragicevic N, Delic V, Cao C, et al. Caffeine increases mitochondrial function and blocks melatonin signaling to mitochondria in _mice and cells. Neuropharmacology. 2012 Dec; 63(8):1368-79.
2- Vaughan RA, Garcia-Smith R, Bisoffi M, Trujillo KA, Conn CA. Effects of caffeine on metabolism and mitochondria biogenesis in rhabdomyosarcoma cells compared with 2,4-Dinitrophenol. Nutrition and Metabolic Insights.
3- Shigenaga MK, Hagen TM, Ames BN. Oxidative damage and mitochondrial decay in aging. Proc Natl Acad Sci U S A. 1994 Nov 8; 91(23):10771-8.
Serving Size: 1 Tablet
Servings per Container: 60
Quantity per Container: 60 Tablets
Amount Per Serving:
|Ingredient||Amount||% Daily Value|
|Vitamin A (100% Beta-Carotene as Betatene® Mixed Carotenoids)||2,500 IU||50%|
|Vitamin C (as calcium ascorbate)||100 mg||167%|
|Vitamin D (as Cholecalciferol)||125 IU||31%|
|Vitamin E (as d-Alpha Tocopheryl Succinate and Mixed Tocopherols)||50 IU||167%|
|Thiamin (Vitamin B1)||7.5 mg||500%|
|Riboflavin (vitamin B2)||7.5 mg||441%|
|Niacin (as Niacinamide)||7.5 mg||38%|
|Vitamin B6 (as pyridoxine HCl)||25 mg||1,250%|
|Folic acid (as Quatrefolic® brand 6S)-5-methyltetrahydrofolate, glucosamine salt and folic acid)||100 mcg||25%|
|Vitamin B12 (as methylcobalamin)||250 mcg||4,167%|
|Pantothenic Acid (as calcium D-pantothenate)||7.5 mg||75%|
|Calcium (as Calcium Citrate, Ascorbate)||50 mg||5%|
|Iron (as Ferrous Bisglycinate Chelate)||2.2 mg||12%|
|Iodine (as potassium iodide)||18 mcg||12%|
|Magnesium (as Magnesium Citrate)||25 mg||6%|
|Zinc (as Zinc Krebs Cycle Complex)‡||3.7 mg||25%|
|Selenium (as L-Selenomethionine)||25 mcg||36%|
|Copper (as copper bisglycinate chelate)||250 mcg||13%|
|Manganese (as Manganese Bisglycinate Chelate)||1.2 mg||60%|
|Molybdenum (as molybdenum glycinate chelate)||37 mcg||49%|
|Potassium (as potassium citrate)||12 mg||<1%|
Mitochondrial Support Proprietary Blend:
Acetyl-L-Carnitine 125 mg, L-Tyrosine 125 mg, N-Acetyl-Cysteine 125 mg, Alpha Lipoic Acid 50 mg, Taurine 50 mg, Coenzyme Q10 (CoQ10) (ubiquinone) 12.5 mg
|Caffeine USP||60 mg||**|
|Mixed Tocopherol Blend||50 mg||**|
|Choline (as Bitartrate)||7.5 mg||**|
|Boron (as boric acid/Krebs cycle intermediate blend‡‡)||250 mcg||**|
Directions and/or Dosage:
Take 1 tablet twice daily with food, or as recommended by your healthcare professional.
Cellulose, Modified cellulose, Modified cellulose gum, Silicon dioxide, Magnesium stearate, Sodium bicarbonate, Citric acid, Vegetable glycerin, Soybean oil.
Does Not Contain:
Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.
Caution: Not recommended for use by pregnant or nursing women or by children under 18 years of age. Do not use if sensitive to caffeine. Each serving of this product contains 60 mg of caffeine. If taking prescription drugs, consult your healthcare professional prior to use.
Complexed with citrate, fumarate, malate, succinate and alpha ketoglutarate.