Researched Nutritionals, Multi-Biome™ 30 Capsules
Two probiotics in one capsule: soil-based spore strains and traditional live strains, six in all.
Most probiotics give you one type of strain, spore or live, so you cover half the picture and refrigerate or restock the other half yourself. Multi-Biome combines both forms in a single delayed-release capsule, with six genomically sequenced strains chosen for their specific characteristics and research-backed benefits.* It is the two-in-one formula doctors and patients reach for when they want soil-based and live-strain support in one bottle.*
- ✓ Spore + non-spore in one. Both forms working together, so you are not buying and timing two separate probiotics.
- ✓ 27 billion CFU, six strains. Promotes healthy microbial balance and supports digestive health.*
- ✓ Delayed-release capsule. Live strains pass through stomach acid intact, where they are meant to work.
- ✓ Supports immune balance. Supports healthy immune function and immune balance, and works via competitive exclusion of harmful bacteria.*
- ✓ Histamine-aware strains. L. rhamnosus GG and B. lactis Bi-07 support healthy histamine levels in the intestine.*
Discount applies automatically at checkout. No code needed. Probiotics work best taken daily over months, so most customers stock up.
Take 1 capsule daily. 30 capsules = a one-month supply.
- ✓ Authorized Researched Nutritionals reseller
- ✓ Secure checkout
- ✓ 30-day returns on unopened bottles
Contains tree nuts (coconut). Made without milk, eggs, fish, shellfish, peanuts, wheat, soy, and gluten.
Discount applies automatically at checkout. No code needed.
Your gut runs on balance. One type of probiotic only covers half of it.
Overall well-being hinges on the balance of your gut. That balance is shaped by the microbes living in your intestine, the helpful ones that keep things running and the ones you want kept in check. Modern life pushes on that balance constantly: the food supply, stress, travel, and the everyday wear of a busy schedule all nudge it off center.
Here is the part most people miss. Probiotic strains come in two broad families. Spore-based (soil-based) strains are rugged. They survive heat, shelf life, and stomach acid, and they help hold the line through competitive exclusion of harmful bacteria.* Traditional live strains (non-spore) are the familiar Lactobacillus and Bifidobacterium that support digestive health and a healthy microbial balance.* Each family does something the other does not.
So when you take a probiotic that is only spore, or only live, you are supporting one side of the balance and leaving the other to chance. Historically, covering both meant buying two separate supplements and keeping one of them in the refrigerator.
"Spore or live is a choice you should not have to make."
When the balance slips, you feel it day to day.
An off-balance microbiome rarely announces itself. It shows up as the small, nagging things that wear on a day:
- Digestion that feels sluggish or unpredictable
- Irregularity you find yourself planning around
- Occasional gas and bloating after meals
- That run-down, "my system is off" feeling
- Reaching for yet another probiotic that only does one job
None of this is your fault, and none of it means starting over. It usually means the balance needs broader support than a single-type probiotic can give.*
Multi-Biome: spore and non-spore, together in one capsule.
Multi-Biome is a Multi-Source Probiotic. It combines spore (soil-based) and non-spore (traditional live strain) probiotics in a single formula, so both families of strains go to work from one daily capsule.
All six strains were selectively chosen for their specific characteristics and research-backed health benefits.* Each one is genomically sequenced and registered, which means strain specificity and safety are confirmed batch after batch, not assumed. This is the two-in-one formula built for doctors and patients who want the benefits of both soil-based and live strains without juggling two bottles.*
It promotes healthy microbial balance, supports digestive health, and supports healthy immune function and immune balance.* No refrigeration. One capsule a day.
- Spore (soil-based) strains that are rugged enough to survive stomach acid and help hold balance
- Non-spore traditional live strains like Lactobacillus and Bifidobacterium that support digestive health
- Six genomically sequenced strains, so strain specificity and safety are confirmed batch after batch
- One capsule a day, no refrigeration, instead of juggling two separate probiotics
"Two probiotics in one. Six strains. One capsule a day."
Why two kinds of probiotic work better than one
Most probiotics give you one kind of organism. Multi-Biome gives you two, because your gut benefits from both, and they do different jobs.
Spore-forming strains: built to arrive
Bacillus subtilis (DE111®) and the two Bacillus coagulans strains are spore-formers. A spore is a protective dormant shell the organism builds around itself, which means these strains are naturally resistant to stomach acid. They stay inert on the way down and activate once they reach the intestine, where they belong.
Non-spore live strains: the traditional workhorses
Lactobacillus rhamnosus (GG), Bifidobacterium lactis (Bi-07), and Lactobacillus salivarius (Ls-33) are the live, traditional strains that decades of probiotic research are built on. Multi-Biome protects them with a delayed-release capsule engineered to hold together through the stomach.
This is the survival problem most probiotics never solve: it is not how many billions go into the capsule, it is how many actually arrive. Spore-formers arrive. The non-spore strains do not form spores, so on their own they are more vulnerable to stomach acid. Multi-Biome solves that with a delayed-release capsule (hypromellose and pectin) engineered to hold together through the stomach and release the live strains where they can take hold. Historically, getting both spore and non-spore benefits meant buying and taking two separate probiotics. This is both in one capsule.
"With a probiotic, the real question was never how many billions are in the capsule. It is how many survive the trip and arrive where they are supposed to work."Dr. Steph, Agape Nutrition
How the formula supports a balanced gut. Beneficial organisms support microbial balance through competitive exclusion, occupying space and resources so the gut environment favors the organisms you want.* Multi-Biome promotes healthy microbial balance and supports digestive health,* and it supports healthy immune function and immune balance,* which makes sense given how much of the immune system lives along the gut wall. The formula also promotes healthy cytokine activity.*
The histamine angle, stated precisely. Two of the non-spore strains, L. rhamnosus GG and B. lactis Bi-07, were selected in part because they support healthy histamine levels in the intestine.* This is a structure/function benefit at the level of the gut. It is not an antihistamine and it is not intended for any histamine-related condition.
Strain specificity is the point. A probiotic benefit belongs to a specific strain, not a species in general. Every strain in Multi-Biome is genomically sequenced and registered, so what is on the label is what is in the capsule, batch after batch. And because the bottle is desiccant-lined to reduce oxygen and moisture, Multi-Biome needs no refrigeration.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary.
Multi-Biome vs. a generic single-type probiotic
Most probiotics pick one lane. Here is what you get when one capsule covers both.
| Feature | Multi-Biome | Generic single-type probiotic |
|---|---|---|
| Spore + non-spore strains together | Yes | No (one or the other) |
| 6 genomically sequenced strains | Yes | ? |
| 27 billion CFU per capsule | Yes | ? |
| Delayed-release capsule for survival past stomach acid | Yes | ? |
| No refrigeration required | Yes | ? (many live-only formulas need it) |
| Supports healthy histamine levels in the intestine* | Yes | No |
| One capsule a day | Yes | ? |
Most single-type probiotics do one job well. Multi-Biome was built to cover both forms in one daily capsule.*
Two probiotics in one. See why doctors and patients choose it.
Get Yours →Spore + non-spore · authentic stock
Everything in the capsule, nothing hidden
Serving size: 1 capsule. 30 servings per bottle. MB Complex delivers 27 billion CFU from six strains:
| Strain | Type | Role (structure/function) |
|---|---|---|
| Bacillus subtilis (DE111®) | Spore-forming | Naturally resistant to stomach acid; supports microbial balance and digestive health by arriving intact in the intestine.* |
| Lactobacillus rhamnosus (GG) | Non-spore live | One of the most extensively studied traditional probiotic strains; supports digestive health and healthy histamine levels in the intestine.* |
| Bifidobacterium lactis (Bi-07) | Non-spore live | Supports digestive and immune balance and healthy histamine levels in the intestine.* |
| Bacillus coagulans (SNZ1969) | Spore-forming | Resists stomach acid; supports microbial balance and digestive health.* |
| Bacillus coagulans (MTCC 5856) | Spore-forming | Genomically registered; supports digestive comfort and a balanced gut environment.* |
| Lactobacillus salivarius (Ls-33) | Non-spore live | Supports microbial balance and healthy immune function.* |
Other ingredients: Rice dextrin, delayed-release capsule (hypromellose, pectin, water), medium chain triglycerides. Vegetarian capsule (hypromellose and pectin, no gelatin).
Showing the 27B blend total only (no invented per-strain CFU). DE111® is a registered trademark of Deerland Probiotics & Enzymes, Inc.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Six strains, 27 billion CFU, printed right on the label.
Add to Cart →$49.98 · 30-day returns on unopened bottles
Simple to take. Easy to keep up.
1 capsule daily
Take 1 capsule daily, with or without food, at whatever time you will remember it.
No refrigeration
The desiccant-lined bottle keeps out oxygen and moisture, so it stores at room temperature.
Caution: If you are pregnant or nursing, or have a question about fit, check with your healthcare professional before use. Individual results vary.
What customers are saying
Real reviews from real customers. Individual results vary.
Join customers supporting their gut, one capsule a day.
Start Today →★ 4.9 from 25 verified reviews
Authentic product. Clear returns. Secure checkout.
Authentic, genuine bottles
The Multi-Biome you order is the genuine product, stored and shipped properly, never a gray-market bottle.
30-day returns
Unopened bottles can be returned within 30 days in their original resalable packaging. Stated honestly up front.
Backed by real customers
4.9 stars from 25 verified reviews, on a two-in-one probiotic people come back to reorder.
Agape Nutrition is an authorized Researched Nutritionals reseller, so the Multi-Biome you order is the genuine product, stored and shipped properly, never a gray-market bottle. Your checkout is secure from cart to confirmation, and it is backed by real customers: 4.9 stars from 25 verified reviews.
- ✓ Unopened bottles can be returned within 30 days in their original resalable packaging (a 15% restocking fee applies, and shipping is non-refundable).
- ✓ For safety reasons, opened probiotics cannot be returned.
- ✓ Reach out for an RMA before sending anything back.
No gimmicks and no fine-print surprises. Authentic product, secure checkout, and a returns policy stated honestly up front.
Practitioner-grade, authentic, and in stock today.
Try It →Authentic bottles · 30-day returns on unopened items
4.9 stars from 25 verified customers
Doctors and patients who switched to a two-in-one probiotic, in their own words.
Rated 4.9 ★ across 25 reviews. Verified by Loox. Liquid build renders the live Loox app block here.
"My naturopath suggested this product and it is a step up from what I was taking and I feel like after a month (this is my second bottle I bought here) I feel so much less fragile and I feel like my stomach and digestion is notably better!"
Lori S. · Verified"Makes my bowels regular."
alison m. · Verified"Instrumental for restoration!"
Carla R. · VerifiedIndividual results vary.
4.9 stars from 25 real customers. See what they reordered.
Get Yours →Real reviews, verified by Loox
Frequently asked questions
What is the difference between spore and non-spore probiotics?
How is this different from a regular probiotic?
Does Multi-Biome need to be refrigerated?
How and when do I take it?
Does it contain any allergens?
Is the capsule vegetarian?
When will I notice results?
What is your return policy?
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Still deciding? Two probiotics in one, one capsule a day. Order now.
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Where the formula comes from
Each strain in Multi-Biome was selected for documented, research-backed characteristics. The published literature on these specific strains informs why they were chosen. References are provided for transparency and education. It does not represent claims that this product produces any specific result. Individual results vary.
- Lactobacillus rhamnosus GG is one of the most extensively studied probiotic strains in the published literature, with a long research history in digestive health.
- Bifidobacterium lactis (Bi-07) is a characterized strain studied for supporting digestive and immune balance.
- Bacillus subtilis (DE111®) is a registered spore-forming strain studied for gut survivability and microbial balance.
- Bacillus coagulans is a spore-forming species with published literature on stomach-acid survival and digestive support.
- Spore-forming vs non-spore probiotics are two recognized categories; spore-formers are documented for gastric-acid resistance.
- Competitive exclusion is an established microbiological concept.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. The research above is provided as educational background and does not constitute a claim about this product's effects. Individual results vary.
Seed the biome, feed it, support the immune side
Practitioners often combine Multi-Biome with these to round out a gut regimen.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary. Consult your healthcare professional before use, especially if pregnant, nursing, taking medication, or managing a medical condition.
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