Bioclinic Naturals, Optimega-3 Q10 | 60 Softgels

Benefits

• Optimal 2:1 ratio EPA to DHA in a highly bioavailable softgel
• Provides 600 mg EPA, 300 mg DHA, and 100 mg CoQ10 per softgel
• Pharmaceutical grade omega-3 blend, USP verified for quality and consistency
• Free of lipid peroxides and environmental pollutants, including heavy metals, pesticides, dioxins, PCBs, and other harmful compounds
• Sourced from wild anchovies, sardines, and/or mackerel, some of the best natural sources of EPA and DHA
• Harvested through sustainable fishing practices

Feature Summary

This high potency combination of CoQ10 and the omega-3 fatty acids EPA/DHA provides cardiovascular and cognitive benefits through multiple distinct and overlapping pathways. Both CoQ10 and EPA/DHA have been shown to improve endothelial function, especially among populations at risk for atherosclerosis (elevated BMI, metabolic syndrome, smoking, hyperlipidemia), with clinically significant hypotensive and anti-atherogenic effects.

CoQ10 has an instrumental role in oxidative phosphorylation and mitochondrial bioenergetics, critical to neuronal health and preventing the mitochondrial dysfunction that underlies numerous chronic diseases, including neurodegenerative disease. Additionally, recent data highlights CoQ10’s emerging role in reducing inflammation and insulin resistance, which are potent contributors to impaired cognitive function. Meta-analysis of randomized trials has shown that CoQ10 and EPA/DHA supplementation reduces key biomarkers of inflammation, including C-reactive protein, TNF-alpha, and IL-6. CoQ10 serum levels have also been associated with neurological outcomes following ischemic stroke, as well as the risk of disabling dementia.

OptiMega-3 Q10 also provides high-dose pharmaceutical grade EPA/DHA, shown to reduce many cardiovascular risk factors and improve vascular function, with controlled clinical trials demonstrating a reduced rate of cardiovascular and coronary events, particularly in persons at high risk. Omega-3 fatty acids have been associated with reduced myocardial infarction, as well as stroke, with supplementation mitigating adverse changes to the left ventricle, myocardial fibrosis, and systemic inflammation following a myocardial infarction. EPA/DHA supports cognitive function through multiple mechanisms, as both are indispensable to neuronal membranes, with lower levels found to be not only a marker for neurological disease but also a risk factor for cognitive impairment.

Non-Medicinal Ingredients

Enteripure® softgel (gelatin, glycerin, purified water, pectin), natural vitamin E.

Dosage

Recommended Adult Dose: 1 softgel 3 times per day or as directed by a health care practitioner.

Warnings

Consult a health care practitioner before use if you are pregnant or breastfeeding, or if you are taking blood thinners or blood pressure medication. Keep out of reach of children.

Allergens

Contains no artificial colors, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, corn, egg, shellfish, salt, tree nuts, or GMOs. Sealed for your protection. Do not use it if the seal is broken. Store in an airtight container, protected from light. For freshness, store in a cool, dry place.

Drug Interactions

Because fish oil has an antithrombotic effect, caution is advised for those on anticlotting, antiplatelet, or anticoagulant medications, or those at high risk of bleeding. However, a multinational randomized and controlled trial found that fish oil did not increase perioperative bleeding, it reduced the number of transfusions needed and appeared to be associated with a lower risk of bleeding when given pre-and postoperatively. At doses greater than 3 g per day, hyperglycemia has been observed in diabetics and those with hypertriglyceridemia, close monitoring of patients on antidiabetic medication is recommended. Benefits have been shown when fish oil is taken with statins, SSRIs, anticonvulsants, and cytotoxic medications. CoQ10 resembles vitamin K structurally, and there is a potential interaction possible for those taking the anticoagulant Coumadin. Close monitoring of the INR is recommended with CoQ10 introduction in these patients.