NeuroScience | Calm CP | 60 Capsules
Calm CP | 60 Capsules:
Decreases cortisol levels and provides ingredients important for calm, sleep, and management of blood sugar*
- Lagerstroemia speciosa (Banaba) leaf extract (2% corosolic acid): Corosolic acid selectively inhibits 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1), an enzyme that catalyzes the conversion of cortisone into cortisol (1,2).* In a randomized study, corosolic acid was shown to significantly lower blood glucose levels by 20-30% after two weeks (3).*
- Phosphatidylserine: Component of cell membranes important for receptor-mediated interactions (4).* Phosphatidylserine is thought to interact with cell membranes in order to dampen hypothalamic signaling and regulate the stress response (5).*
- Glycine: Major inhibitory neurotransmitter that crosses the blood-brain barrier (6).* Binds receptors that regulate temperature during sleep (7).*
- Taurine: Neuro protective amino acid that provides antioxidant protection and demonstrates GABA-A agonist activity (8-10).* GABA is the primary inhibitory neurotransmitter in the brain important for calm and sleep (11-13).
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Serving Size: 2 Capsules
Servings Per Container: 30
Amount Per Serving:
|Ingredient||Amount||% Daily Value|
Lagerstroemia speciosa (Banaba) leaf extract (2% corosolic acid), Phosphatidylserine enriched soy lecithin*, Glycine, and Taurine
† Daily Value not established.
Take 2 capsules one to two times daily or as directed by your healthcare provider.
Vegetable capsule (Hypromellose, water), Microcrystalline cellulose, Magnesium stearate (vegetable source), and Silicon dioxide.
If you are pregnant or nursing, consult your healthcare provider before use. Contains lecithin from soy.
1. Rollinger J, et al. Bioorg Med Chem. 2010;18(4):1507-15.
2. Patel H, et al. Arabian Journal of Chemistry. 2015.
3. Judy W, et al. J Ethnopharmacol. 2003;87(1):115-7.
4. Monteleone P, et al. Eur J Clin Pharmacol. 1992;41:385-8.
5. Glade M and Smith K. Nutrition. 2015;31(6):781-6.
6. Kawai N, et al. Amino Acids. 2012;42(6):2129-37.
7. Kawai N, et al. Neuropsychopharmacology. 2015;40(6):1405-16.
8. Kumari N, et al. Adv Exp Med Biol. 2013;775:19-27.
9. Shimada K, et al. Adv Exp Med Biol. 2015;803:581-96.
10. Kletke O, et al. PLoS One. 2013;8(4):e61733.
11. Gou Z, et al. Dongwuxue Yanjiu. 2012;33(E5-6):E75-81.
12. Mohler H. Neuropharmacology. 2012;62(1):42-53.
13. Saper C, et al. Nature. 2005;437(7063):1257-63.