Prodrome Sciences

Created by Founder and CEO Dr. Dayan Goodenowe

Inventor. Biochemist. Neuroscientist. Synthetic organic chemist. International speaker. Entrepreneur.

Dr. Goodenowe invented an advanced mass spectrometry technology platform in 1999 that has been used to analyze thousands of human samples from around the world and continues to be the most advanced technology of its kind today. Using this technology, he established collaborations with world-renowned international researchers and physicians in dementia, Alzheimer’s, Parkinson’s, multiple sclerosis, colorectal cancer, pancreatic cancer, ovarian cancer, breast cancer, bipolar disorder, schizophrenia, and several other diseases. Dr. Goodenowe is an expert on the biochemical basis of disease. His passion is targeted optimization of human biochemistry for longevity and vitality.

Which diseases are linked to low plasmalogns?

• Alzheimer’s disease results from neurodegeneration of neurons responsible for cognition: cholinergic neurons. Cholinergic neurons are especially sensitive to decreased membrane fusion activity caused by plasmalogen deficiency because, unlike other neurons, membrane fusion is necessary for both neurotransmitter release and re-uptake. Reduced membrane fusion reduces neurotransmission which reduces cognition.

• Parkinson’s disease results from neurodegeneration of neurons responsible for fine motor control: dopaminergic neurons. The direct cause of Parkinson’s is unknown, but some environmental neurotoxins selectively target dopaminergic neurons and cause Parkinson’s in animals. Plasmalogen deficiency increases susceptibility to neurotoxins.

• Multiple Sclerosis results from neurodegeneration of cells that insulate neurons: myelin or oligodendrocytes. Myelin has the highest concentration of plasmalogens in the whole body. When immune cells are activated to clean up a mess (inflammation), part of the myelin can be damaged and extra plasmalogens are needed to repair the cells before they die. If cells cannot be repaired before they die, the debris creates even more inflammation and degeneration. High levels of plasmalogens prevent demyelination by improving remyelination.

Why do you need plasmalogens?

• Plasmalogens are essential molecules for the cells in our bodies.

• These cells have vital roles in the brain, heart, lungs, kidneys, and eyes.

• As we increase in age, these cells decrease in quantity.

• Studies have shown that the decrease in these molecules may be related to the symptoms of brain diseases.

• Plasmalogens are naturally inside us, so you can rest assured by supplementing plasmalogens.