XYMOGEN, ALAmax™ CR 120 Tablets

XYMOGEN®

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Antioxidant

ALAmax™ CR is a whole-body, multifunctional antioxidant that helps to maintain healthy, well-functioning cells. ALAmax CR is designed to neutralize free radicals. ALAmax CR has the ability to destroy free radicals in both the water-based and lipid-based portion of cells, making it the ideal whole-body antioxidant. In addition, ALAmax CR...
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ALAmax CR is a whole-body, multifunctional antioxidant that helps to maintain healthy, well-functioning cells. ALAmax CR is designed to neutralize free radicals. ALAmax CR has the ability to destroy free radicals in both the water-based and lipid-based portion of cells, making it the ideal whole-body antioxidant. In addition, ALAmax CR helps the body synthesize glutathione, the body’s own master detoxifier. ALAmax CR also “recharges” other important antioxidants, such as vitamins C and E, and CoQ10, giving them the ability to continue fighting free radicals for extended periods of time.  In addition, biotin supports the function of alpha-lipoic acid in regulating glucose metabolism.*

Alpha-lipoic acid (ALA) is an eight-carbon disulfide water- and fat-soluble compound that is synthesized in small quantities in the liver and other tissues. Oral supplementation readily crosses the blood-brain barrier after it is absorbed in the small intestine, goes into the portal vein, and is distributed via systemic circulation. Once in the tissues, ALA can be found inside and outside the cells including inside the mitochondria where it functions naturally as a coenzyme for the oxidation of pyruvate, alpha-ketoglutarate, and branched-chain amino acids.*

Researchers recently identified lipoic acid’s mechanisms of action related to maintaining metabolic health. It has a direct binding site at the insulin receptor tyrosine kinase domain. ALA appears to modulate 5’-AMP-activated protein kinase and PPAR-regulated genes, to activate PPAR–alpha and PPAR-gamma, and to support the expression of PPAR-gamma mRNA and protein in heart tissue and smooth muscle of the aorta.*[2] 

Controlled-release technology supports the efficacy of alpha-lipoic acid in helping to maintain blood sugar already in the normal range. Data from a 12-week clinical study indicate that supplementation with ALAmax™ CR (1200 mg per day, divided doses) may support healthy C-peptide levels. C-peptide is used as an indication of insulin sensitivity.*[3,4]

Alpha-lipoic acid effectively neutralizes a variety of free radicals, including oxygen radicals and ionized metals. This action is particularly beneficial for people with higher oxidative stress levels. Alpha Lipoic acid regenerates vitamins C and E, increases tissue levels of glutathione, and helps maintain the proper ratio of reduced to oxidized coenzyme Q10 in the mitochondria. In addition, alpha-lipoic acid may help the body rid itself of heavy metals.*

Healthy endothelial-mediated vasodilation is accepted as a surrogate marker for cardiovascular health and can be affected by the synthesis, bioavailability, or action of nitric oxide (NO). Increased oxidative stress plays a significant role in neutralizing or inactivating NO. ALA’s antioxidant properties, along with its demonstrated safety and potency, qualify it as a prime candidate to evaluate for its ability to support healthy endothelial function.*[5]

The ability of alpha-lipoic acid to improve energy metabolism and decrease oxidative stress alludes to its ability to support healthy mitochondrial function with age.*

Biotin has been added because chronic administration of lipoic acid lowers the activities of pyruvate carboxylase and beta-methylcrotonyl CoA carboxylase in vivo by competing with biotin.*[6]

  • Provides Fat-Soluble and Water-Soluble Antioxidant Activity*
  • Coenzyme for Whole-Body Glucose Utilization*
  • Supports Healthy Intracellular Glutathione Levels*
  • Supports Regeneration of Vitamins C and E*
  • Helps Maintain a Balance Between Oxidized and Reduced CoQ10*

 

Other Ingredients:

Hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, hydroxypropyl cellulose, dicalcium phosphate, silica, and coating (hydroxypropyl methylcellulose and medium-chain triglycerides).

Directions:

Take one tablet 30 minutes before breakfast and one tablet 30 minutes before dinner, as directed by your healthcare professional. Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professionals. Do not use it if the tamper seal is damaged.

Storage:

Keep closed in a cool, dry place out of reach of children.

Formulated To Exclude:

Wheat, gluten, yeast, corn, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, eggs, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.

References:

  1. Teichert J, Kern J, Tritschler HJ, Ulrich H, Preiss R: Investigations on the pharmacokinetics of alpha-lipoic acid in healthy volunteers. Int.J.Clin. Pharmacol. Ther. 36:625-628, 1998
  2. Pershadsingh HA. Alpha-lipoic acid: physiologic mechanisms and indications for the treatment of the metabolic syndrome. Expert Opin Investig Drugs. 2007 Mar;16(3):291-302 [PMID: 17302524]
  3. Evans JL, Goldfine ID: α-Lipoic acid: a multifunctional antioxidant that improves insulin sensitivity in patients with type 2 diabetes. Diabetes Technol Therap 2:401-413, 2000
  4. Jacob S, Ruus P, et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type 2 diabetes mellitus: a placebo-controlled pilot trial. Free Radic Biol Med 27:309-314, 1999
  5. Bojunga J, et al. Antioxidative treatment reverses imbalances of nitric oxide synthase isoform expression and attenuates tissue-cGMP activation in diabetic rats. Biochem Biophys Res Commun. 2004 Apr 9;316(3):771-80 [PMID: 15033467]
  6. Zempleni J, Trusty TA, Mock DM. Lipoic acid reduces the activities of biotin-dependent carboxylases in rat liver. J Nutr. 1997 Sep;127(9):1776-81 [PMID: 9278559]
  7. Foster TS. Efficacy and safety of {alpha}-lipoic acid supplementation in the treatment of symptomatic diabetic neuropathy. Diabetes Educ. 2007 JanFeb;33(1):111-7 [PMID: 17272797]
  8. Alpha Lipoic Acid. www.naturaldatabase.com {accessed 3.06.07}
  9. Diesel B. et. al. Alpha-lipoic acid as a directly binding activator of the insulin receptor: protection from hepatocyte apoptosis. Biochemistry. 2007 Feb 27;46(8):2146-2155. Epub 2007 Feb 3 [PMID: 17274632]

 

Agape Nutrition is proud to offer:

United States Postal Service (USPS) and United Parcel Service (UPS) as our standard shipping carriers and their services. Shipping rates are determined in real time or carrier book rate by weight and distance. Shipping Options are determined and reflected upon check out, for your choosing. If an option is not listed upon check out, your package may not meet the weight requirement or the service may not be available to the address location. Automated invoices for orders and shipping updates will drop into the email listed on the Agape Nutrition account. If SMS is accepted, automated updates will go to your phone via text message, you may also receive an email.

 

We pride ourselves on providing fast service at competitive prices.

  • Orders received by 12:00 pm Pacific Standard Time (PST) are generally processed the same day, and may ship within 24 hours. However, this is not a guarantee.
  • Orders received after 12:00 PM (PST) may process within 24 to 48 hours of receipt.
  • Tracking is updated within 24 to 48 hours of receipt and after processing and the package has shipped.

 

Processing and shipping times are:

  • Estimated and applicable during regular business hours.
  • Dependent upon the daily order volume at Agape Nutrition.
  • Dependent upon the daily order volume at the partner warehouse.
  • Dependent upon the time zones of our manufacture and distributor partners.
  • Dependent upon the shipping service practices and processing standards.

 

 

USPS Holiday Schedule             Agape Nutrition Holiday Schedule                 UPS Holiday Schedule

USPS  (Business Days) UPS (Business Days)
USPS Priority Mail (1-3 Business Day) UPS 2nd Day Air (2 Business Day)
 USPS Parcel Select (1-7 Business Day ) UPS 3 Day Select (1-3 Business Day)
USPS First Class Package (1-3 Business Day) UPS Ground (1-7 Business Day)

 Please Note: No Saturday Delivery Available.

 

Signature may be required for:

  • Orders of a high dollar amount.
  • Biotics Research shipments.
  • Vielight shipments.
  • Richway shipments.
  • All electronic devices.
  • All laboratory test kits.

 

 We have fixed shipping rates for a select few brand partners as per their shipping rate requirements, which may be different then our own and other distributor warehouses. Brands that apply: Vielight, Richway International, Biotics Research.

Shipping carriers are experiencing delays. This is due to increased shipments resulting from the COVID-19 pandemic combined with any holidays, and / or natural disasters.

Expedited shipping (2-Day, 3-Day, and Next-Day) are not guaranteed by the carriers and does not include weekend delivery. Due to no carrier guarantees, delayed or late packages are not eligible for refunds. This is a stipulation directly from the shipping carriers and is out of our control.

Shipping Service Guarantees Remain Suspended for Most Shipments. Please reach out to the shipping carrier for more information.

 

SHIPPING DISCOUNTS

 

Please see our FAQ page for additional questions and answers.

All discounts and promotional offers are calculated before shipping and handling rates are applied.


ORDER CANCELLATIONS

Orders cannot be cancelled or changed once the order has been placed and the confirmation is received.

Products may ship faster then expected, and many are automated to process directly after order confirmation. We work directly with top professional manufactures and distributors from across the United States, in all time zones. There are a lot of cogs and wheels turning to process and ship your order efficiently to meet an on time delivery target. When you request a cancellation or change of an order, it may take up to 72 hours to process your request. This process may involve voiding orders in computer systems, removing items from back order logs, pulling items from production schedules and sometimes stopping orders at the shipping dock or warehouse. Our order fulfillment may be performed by many quick hands, in different states and time zones. Therefore, we cannot offer or guarantee order cancellations after the order has been received.

  • Products may process and ship faster then expected.
  • Products may be automated to process directly after the order is confirmed.
  • Product warehouses may be in different states and time zones.
  • Orders may take up to 72 hours to process a cancellation or change. 

 

 DOMESTIC SHIPMENTS

Agape Nutrition is proud to ship to 52 states and territories of the United States.

  • All 50 United States (includes Washington DC, Hawaii, Alaska)
  • Armed Forces: Americas (AA)

Orders shipped to U.S. military addresses (APO/FPO/DPO) will ship via United States Postal Service (USPS) at the carrier book rate; normal delivery of these orders may be delayed by one (1) business day.

 

INTERNATIONAL SHIPMENTS
Agape Nutrition does not offer international shipping at this time, outside the 52 states, including Washington DC and Armed Forces Americas of the United States.

 

HEAT SENSITIVE SHIPMENTS
Products requiring shipment in a cool environment (perishable and frozen items) are subject to special shipping procedures due to their sensitive nature to ensure customers receive products in good condition. Heat sensitive items are shipped using sealed thermal bubble bag, ice pack or brick, resealable bag and extra padding to ensure a cool environment. We do not recommend heat sensitive item ship to territories of the United States, and we cannot be held responsible for cooled environment degradation to these destinations.

Agape Nutrition recommends that heat sensitive products ship with your preference of any 1-3 Day delivery service. We do not offer overnight or next day delivery service at this time. Saturday delivery is not available or guaranteed, unless offered by the shipping carrier as part of the normal delivery.

Please Note:

  • Heat sensitive items are not eligible for return, credit, or refund. As we cannot guarantee cool storage or efficacy of the product, after the order has been delivered.
  • Delays in shipping service delivery, caused an issue? See our return policy for further information.

       

      PACKAGE DELAYS

      Please be aware of severe weather and hazardous conditions in your area or other states that may affect the timeliness of your package delivery. Agape Nutrition can not be responsible for severe weather and unforeseen incidents that may impact the processing times and/or shipping services. We will work to ensure the safety of our employees while minimizing effects on service. Contingency plans are in place to help ensure that shipments arrive at their final destinations as quickly as conditions permit.

       

      Please Be Aware of Any Possible Shipping Delays:

      (1) Slight delays with fulfillment processing may occur as manufacture and distributor warehouses are experiencing higher than normal volume and demand for nutritional items.

      (2) Shipping carriers are experiencing delays. This is due to increased shipments resulting from the COVID-19 pandemic combined with any holidays, and/or natural disasters. Expedited shipping (2-Day, 3-Day, and Next-Day) are not guaranteed by the carriers and does not include weekend delivery. Please reach out to the shipping carrier for more information.

      (3) Please be aware of severe weather conditions in or around your location and surrounding states that my affect the timeliness of delivery.

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