Bioclinic Naturals, Myo-Inositol Plus 60 Servings

Benefits

• Provides recommended 40:1 ratio of myo-inositol to D-chiro-inositol
• Contains naturally occurring forms of inositol
• Includes methylcobalamin and activated folate (L-5-MTHF) for healthy fertility and pregnancy*
• Adequate folate in healthful diets may reduce a woman’s risk of having a child with a brain or spinal cord birth defect
• Unflavored powder allows for easy twice-per-day dosing

Feature Summary

Myo-Inositol Plus provides the two most common, naturally occurring, and complementary forms of inositol: myoinositol and D-chiro-inositol. Both forms of inositol have been shown to support ovarian, metabolic, and endocrine function in women.*

Myo-inositol and D-chiro-inositol have been shown to support both ovarian function, including cycle regularity and normal LH levels, and metabolic function, including HOMA index and insulin.* Additionally, D-chiro-inositol supports endocrine functions such as normal androgen levels, as well as blood pressure already within the normal range.*1-9

In Myo-Inositiol Plus, these complementary nutrients are combined in the 40:1 ratio that has been recommended by the International Consensus Conference on Myo-inositol and D-chiro-inositol. 10

This product also contains methylcobalamin and activated folate (L-5-MTHF) for healthy fertility and pregnancy,* both of which are active forms that do not require metabolism for use. Adequate folate in healthful diets may reduce a woman’s risk of having a child with a brain or spinal cord birth defect.

Suggested Usage

Adults: Stir 1 scoop (2.15 g) into 250 ml of water 1–2 times per day or as directed by a healthcare professional.

Allergens

Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.

Contraindications

Do not use if you are taking immunosuppressive drugs and/or if you are pregnant or breastfeeding. Do not drive or use machinery for 5 hours after taking melatonin.

Drug Interactions

Myo-inositol has been shown to enhance the efficacy of clomiphene. When given folic acid, it improved ovulation rates (65.5%) compared to clomiphene alone (42%), as well as pregnancy rates (53.8% combined use vs. 42.2% clomiphene alone).11 Medication dosage to control hyperglycemia may need monitoring, as myo-inositol benefits insulin sensitivity like metformin.12

Warnings

Consult your healthcare professional prior to use if you are pregnant, trying to become pregnant, breastfeeding, taking medication,  have a medical condition, or anticipate surgery. Keep out of the reach of children.

References

1. Gerli, S., Papaleo, E., Ferrari, A., et al. (2007). Eur Rev Med Pharmacol Sci, 11(5), 347-354.
2. Unfer, V., Facchinetti, F., Orrù, B., et al. (2017). Endocr Connect, 6(8), 647-658.
3. Costantino, D., Minozzi, G., Minozzi, E., et al. (2009). Eur Rev Med Pharmacol Sci, 13(2), 105-110.
4. Nordio, M., & Proietti, E. (2012). Eur Rev Med Pharmacol Sci, 16(5), 575-581.
5. Colazingari, S., Treglia, M., Najjar, R., et al. (2013). Arch Gynecol Obstet, 288(6), 1405-1411.
6. Pizzo, A., Laganà, A.S., & Barbaro, L. (2014). Gynecol Endocrinol, 30(3), 205-208.
7. Formuso, C., Stracquadanio, M., & Ciotta, L. (2015). Minerva Ginecol, 67(4), 321-325.
8. Laganà, A.S., Barbaro, L., & Pizzo, A. (2015). Arch Gynecol Obstet, 291(5), 1181-1186.
9. Genazzani, A.D., Santagni, S., Rattighieri, E., et al. (2014). Gynecol Endocrinol, 30(6), 438-443.
10. Facchinetti, F., Bizzarri, M., Benvenga, S., et al. (2015). Eur J Obstet Gynecol Reprod Biol, 195, 72-76.
11. Rolland, A.L., Peigné, M., Plouvier, P., et al. (2017). Eur Rev Med Pharmacol Sci, 21(2 Suppl), 10-14.
12. Fruzzetti, F., Perini, D., Russo, M., et al. (2017). Gynecol Endocrinol, 33(1), 39-42.