Left Continue shopping
Your Order

You have no items in your cart

Professional Supplements & Nutritional Products Since 1998

Neo40® is our flagship Nitric Oxide product, clinically shown to support healthy blood pressure, circulation, and energy. Backed by six peer-reviewed, randomized, placebo-controlled trials, Neo40® features a patented, dual-action formula that helps quickly restore and sustain Nitric Oxide levels. It’s the most scientifically studied Nitric Oxide lozenge—and recommended by thousands of healthcare professionals.

Functional Benefits

  • Helps increase Nitric Oxide
  • Promotes healthy blood flow & circulation
  • Supports healthy blood pressure
  • Supports cardiovascular health

Ingredients

Beetroot from non-GMO beetroot powder that helps support Nitric Oxide production through the nitrate-nitrite pathway.

Hawthorn Berry Extract contains high levels of antioxidants (polyphenols) that help activate the key enzyme eNOS, which helps your body quickly convert L-arginine to Nitric Oxide. It also helps reduce nitrite to Nitric Oxide.

5-MTHF (5’-Methyltetrahydrofolic acid) is used in the synthesis of BH4. Maintaining sufficient levels of this very important cofactor is necessary for the proper function of eNOS. If the level of tetrahydrobiopterin is not maintained, the enzyme becomes uncoupled and generates free radicals rather than Nitric Oxide.

Sodium Nitrite is quickly converted to Nitric Oxide by hawthorn berry extract and has clinically significant vasodilator activity.

L-citrulline is an effective substitute source for L-arginine, which eNOS converts to Nitric Oxide. It also inhibits arginase, which removes L-arginine from circulation. This then reduces Nitric Oxide production.

Vitamin B12 reduces direct inhibition of eNOS by homocysteine and production of ADMA (asymmetrical dimethyl-arginine), and helps replenish tetrahydrobiopterin.

Vitamin C helps prevent the removal of Nitric Oxide by free radicals and removes free radicals that inhibit eNOS.

The Science

Neo40® is the first dual-pathway Nitric Oxide technology, designed to restore and sustain Nitric Oxide levels as they naturally decline with age. It works through two mechanisms: the nitrate-nitrite reduction pathway, which converts dietary nitrates into nitrite and then into Nitric Oxide; and the enzymatic pathway, which activates endothelial nitric oxide synthase (eNOS) for rapid, consistent production. Backed by more than 15 years of research and patented technology developed in partnership with The University of Texas Health Science Center.

Suggested Use

Place one tablet in your mouth and let it dissolve.

We recommend an initial Nitric Oxide restoration loading period. During the first 30 to 45 days, take one tablet two times a day, or every 12 hours. This could be one in the morning and one in the evening.

Other Ingredients

Mannitol, xylitol, modified cellulose, magnesium, vegetable stearate, natural flavor, silica, and stevia.

Other Features and Attributes

Neo40® is gluten-free, soy-free, dairy-free, caffeine-free, sugar-free, non-GMO, and contains no artificial sweeteners. It is third-party tested for purity, potency, and safety.