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Professional Supplements & Nutritional Products Since 1998

Decreases cortisol levels and provides ingredients important for calm, sleep, and management of blood sugar*

  • Cortisol Health & Adrenal Support - Calm CP is designed for adrenal support, to lower cortisol and provide ingredients important for calm and rest.* This groundbreaking blend includes phosphatidylserine, banaba leaf standardized to 18% corosolic acid, glycine and a taurine supplement.
  • Shown to Help Lower Cortisol for Women & Men - In a survey on the effectiveness of Calm CP, participants were prescreened for elevated cortisol levels. Calm CP was shown to reduce cortisol (mean daily cortisol) by 17%.*
  • Stress Support - High stress has been linked to less healthy dietary behaviors and elevated bedtime cortisol levels are associated with increased abdominal fat.* Calm CP is designed to address body management and the stress response, in which Cortisol plays a major role.*
  • Promote Peaceful Nights - Calm CP includes a glycine supplement: This amino acid neurotransmitter binds receptors that regulate temperature during the night.* Taurine helps the body's natural GABA levels function more efficiently. GABA offers calm support and is the primary inhibitory neurotransmitter in the brain that is important for restful nights.*
  • Practitioner Trusted, Professional Grade - Trusted by thousands of healthcare professionals, NeuroScience formulates products of adrenal support supplements, brain support, and immune health supplements exclusively on peer-reviewed research.* All are USA-manufactured in a cGMP-compliant facility.*

Key ingredients:

  • Lagerstroemia speciosa (Banaba) leaf extract (2% corosolic acid): Corosolic acid selectively inhibits 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1), an enzyme that catalyzes the conversion of cortisone into cortisol (1,2).* In a randomized study, corosolic acid was shown to significantly lower blood glucose levels by 20-30% after two weeks (3).*
  • Phosphatidylserine: Component of cell membranes important for receptor-mediated interactions (4).* Phosphatidylserine is thought to interact with cell membranes to dampen hypothalamic signaling and regulate the stress response (5).*
  • Glycine: Major inhibitory neurotransmitter that crosses the blood-brain barrier (6).* Binds receptors that regulate temperature during sleep (7).*
  • Taurine: Neuro-protective amino acid that provides antioxidant protection and demonstrates GABA-A agonist activity (8-10).* GABA is the primary inhibitory neurotransmitter in the brain important for calm and sleep (11-13).

Supplement Facts:

Serving Size: 2 Capsules
Servings Per Container: 30

Amount Per Serving:

Ingredient Amount % Daily Value
Proprietary Blend
Lagerstroemia speciosa (Banaba) leaf extract (2% corosolic acid), Phosphatidylserine enriched soy lecithin*, Glycine, and Taurine
1.2 g

† Daily Value not established.

Suggested Use:

Take 2 capsules one to two times daily or as directed by your healthcare provider.

Other Ingredients:

Vegetable capsule (Hypromellose, water), Microcrystalline cellulose, Magnesium stearate (vegetable source), and Silicon dioxide.


If you are pregnant or nursing, consult your healthcare provider before use. Contains lecithin from soy.

*The Food and Drug Administration has not evaluated these statements. This product is not intended to diagnose, treat, cure, or prevent any disease.

1. Rollinger J, et al. Bioorg Med Chem. 2010;18(4):1507-15.
2. Patel H, et al. Arabian Journal of Chemistry. 2015.
3. Judy W, et al. J Ethnopharmacol. 2003;87(1):115-7.
4. Monteleone P, et al. Eur J Clin Pharmacol. 1992;41:385-8.
5. Glade M and Smith K. Nutrition. 2015;31(6):781-6.
6. Kawai N, et al. Amino Acids. 2012;42(6):2129-37.
7. Kawai N, et al. Neuropsychopharmacology. 2015;40(6):1405-16.
8. Kumari N, et al. Adv Exp Med Biol. 2013;775:19-27.
9. Shimada K, et al. Adv Exp Med Biol. 2015;803:581-96.
10. Kletke O, et al. PLoS One. 2013;8(4):e61733.
11. Gou Z, et al. Dongwuxue Yanjiu. 2012;33(E5-6):E75-81.
12. Mohler H. Neuropharmacology. 2012;62(1):42-53.
13. Saper C, et al. Nature. 2005;437(7063):1257-63.