NeuroScience, Calm G 90 Capsules

Contains a blend of ingredients important for regulating glutamate activity, stress reduction, metabolic health, and mitochondrial function*

• Is an Overactive Immune System Keeping You Stressed? Long-term immune activation can lead to imbalances that can contribute to anxiousness, fatigue, low mood, and sleep difficulties.*
• A New Approach to Calm - Calm G contains ingredients important for regulating glutamate activity, stress reduction, metabolic health, and mitochondrial function.* While common calm aids can act more like a band-aid, this unique blend is designed to fight stress at a deeper, cellular level.*
• Antioxidants to Combat Immune Activation - Oxidative stress is directly linked to immune activation. Calm G combats oxidative stress with powerful antioxidants alpha-lipoic acid, and coenzyme Q10 (CoQ10).
• Reduce Stress + Glutamate Activity - Glutamate activity is associated with anxiousness and stress. In a double-blind, placebo-controlled study, L-theanine (a glutamate receptor blocker) was shown to significantly reduce stress.*
• Practitioner Trusted, Professional Grade - Trusted by thousands of healthcare professionals, NeuroScience formulates products exclusively on peer-reviewed studies. All products are USA manufactured in a cGMP-compliant facility.

Key ingredients:

• N-acetyl-L-cysteine: Precursor to L-cysteine, which is required for the synthesis of glutathione, an endogenous antioxidant important for mediating oxidative stress (1,2).*  L-cysteine modulates glutamate activity through the activation of cystine/glutamate antiporters (3).
• L-theanine: Amino acid that acts as a glutamate receptor antagonist (4).* Glutamatergic signaling underlies mechanisms related to anxiousness and stress (5). In a double-blind, placebo-controlled study, L-theanine was shown to significantly reduce stress (6).*
• Alpha-lipoic acid: Antioxidant that is able to regenerate endogenous antioxidants and scavenge metal ions and free radicals (7).* Evidence suggests the insulin-signaling pathway is sensitive to redox status (7). Alpha-lipoic acid can influence the redox status in cells important for the translocation of glucose transporters and increasing glucose uptake (7).*
• Coenzyme Q10: Compound found in nearly every human cell that is essential for mitochondrial function and antioxidant protection (8).*

Supplement Facts:

Serving Size: 2 Capsules
Servings Per Container: 45

Amount Per Serving:

†Daily Value not established.

Suggested Use:

Take 1-2 capsules three to four times daily or as directed by your healthcare provider.

Other Ingredients:

Microcrystalline cellulose, Vegetable capsule (Hypromellose, water), and Magnesium stearate (vegetable source).

Notes/Warnings:

If you are pregnant or nursing, consult your healthcare provider before use.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

References:

1. Rushworth G and Megson I. Pharmacol Ther. 2014;141(2):150-9.
2. Schmitt B, et al. Redox Biol. 2015;6:198-205.
3. Berk M, et al. Trends Pharmacol Sci. 2013;34(3):167-77.
4. Kakuda T, et al. Biosci Biotechnol Biochem. 2002;66(12):2683-6.
5. Bermudo-Soriano C, et al. Pharmacol Biochem Behav. 2012;100(4):752-74.
6. Kimura K, et al. Biol Psychol. 2007;74(1):39-45.
7. Rochette L, et al. Can J Physiol Pharmacol. 2015;93(12):1021-7.
8. Garrido-Maraver J, et al. Front Biosci (Landmark Ed). 2014;19:619-33.