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Professional Supplements & Nutritional Products Since 1998

Contains a blend of ingredients important for mood and sleep-wake function*

  • Mood Support - Experience serenity without sacrificing everyday energy or productivity levels. Serene contains a blend of 5-HTP + vitamins important for mood and sleep.*
  • Serotonin Support - Active forms of vitamin B6, folate, and C are important for the creation of serotonin, which is important for regulating mood.*[2-7]
  • Improve Mood - In a randomized, double-blind study, 5-HTP was shown to improve mood significantly.*[8]
  • Practitioner Trusted, Professional Grade - Trusted by thousands of healthcare professionals, NeuroScience formulates products exclusively on peer-reviewed studies. All products are USA manufactured in a cGMP-compliant facility.

Key ingredients:

  • 5-HTP (from Griffonia simplicifolia seed extract):  5-hydroxytryptophan (5-HTP) crosses the blood-brain barrier and is a precursor to serotonin and melatonin (1).* Serotonin is important for regulating mood and sleep-wake function (2). In a randomized, double-blind study, 5-HTP was shown to significantly improve mood (3).*
  • Vitamins B and C: Active forms of vitamin B6, folate, and C are important for serotonin synthesis (4-8).*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts:

Serving Size: 1 Capsule
Servings Per Container: 60

Amount Per Serving:

Ingredient Amount % Daily Value
Vitamin C (as ascorbic acid) 300 mg 500%
Vitamin B6 (as pyridoxal 5'- phosphate) 2.5 mg 125%
Folate (as (6S)-5-methyltetrahydrofolic acid) (equivalent to 205 mcg of (6S)-5-methyltetrahydrofolic acid, glucosamine salt**) 133 mcg 33%
Calcium (as calcium citrate) 74 mg 7%
5-hydroxytryptophan (from Griffonia simplicifoliaseed extract) 100 mg

†Daily Value (DV) not established.

Suggested Use:

Take 1 capsule one to two times daily or as directed by your healthcare provider.

Other Ingredients:

Vegetable capsule (Hypromellose, water), Microcrystalline cellulose, and Magnesium stearate (vegetable source).

Notes/Warnings:

If you are pregnant or nursing, consult your healthcare provider before use.

References:

  1. Shaw K, et al. Cochrane Database Syst Rev. 2002;(1): CD003198.
  2. Monti J. Sleep Med Rev. 2011;15(4):269-81.
  3. Jangid P, et al. Asian J Psychiatr. 2013;6(1):29-34.
  4. Dakshinamurti K, et al. Ann N Y Acad Sci. 1990;585:128-44.
  5. Bottiglieri T. Psychiatr Clin North Am. 2013;36(1):1-13.
  6. Stahl S. J Clin Psychiatry. 2008;69(9):1352-3.
  7. Antoniades C, et al. Circulation. 2006;114(11):1193-201.
  8. May J, et al. Brain Res Bull. 2013;90:35-42.