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Professional Supplements & Nutritional Products Since 1998

Enzy-Gest is a powerful two-phase digestive enzyme supplement formula. It provides enzymes to maintain healthy digestion and intestinal enzyme activity. Enzymes promote absorption in a healthy gastrointestinal tract.*

Exclusive Enteric Matrix Formula Allows for pH-Sensitive Release.

Different enzymes are active at different pH levels. The Enzy-Gest and Hypo-Gest’s exclusive enteric matrix formulation allows for a two-phase, pH-sensitive release of enzymes. The first phase is released in the stomach (gastric phase) and the second in the upper intestine (enteric phase).

Proper digestion is necessary for optimum health. Not only are foods and nutritional substances of little benefit when breakdown and assimilation are inadequate, but incompletely digested food molecules can also be inappropriately absorbed into systemic circulation due to temporary indigestion.

Enzymatic action originates in four areas: the salivary glands, the stomach, the pancreas, and the wall of the small intestine. Each enzyme breaks down only a specific substance. For example, an enzyme capable of breaking down fats cannot break down proteins or carbohydrates and vice versa.1

Gastric Phase Releases Pepsin, Papain, and Needed Acids

The stomach is primarily responsible for the digestion of proteins and the ionization of minerals. The stomach secretes gastric acid, (hydrochloric acid) and various hormones and enzymes.2

In Enzy-Gest and Hypo-Gest, the gastric release phase supplies the protein digestive enzymes pepsin and papain. Betaine HCI (a source of hydrochloric acid) and glutamic acid provide the stomach with the necessary acids to support healthy digestion.

Papain - is a protein-digesting enzyme isolated from the unripe papaya fruit.

Pepsin – Aids with another function of the stomach breaking down large proteins into smaller peptides and peptones. The stomach’s acidic environment harbors few enzymes. The primary enzyme in the stomach, pepsin, is used to digest proteins. Pepsin breaks up proteins into smaller peptides of varying lengths.

Several studies have shown that the ability to secrete gastric acid decreases with age. Low stomach acidity has been found in over half of people over age 60. 2-4

Common symptoms of low gastric acidity include the following:

  • Bloating, belching, burning, and flatulence immediately after meals2
  • A sense of "-fullness-" after eating2
  • Occasional indigestion, diarrhea, or constipation2
  • Undigested food in the stool2
  • Upper digestive tract gassiness2


Enteric Phase Releases Digestive Enzymes and Bile

Regarding pancreatin,  in a study on the therapeutic response of oral enzymes, researchers concluded that ...” the administration of these high potency digestive aids, along with meals, doesn't have a positive clinical influence on reducing malabsorption through improved digestion…when comparing a healthy pancreatic sufficient individual to one with pancreatic insufficiency, the use of pancreatin with meals greatly increases the fat splitting enzyme activity in the duodenum to nearly normal levels.”5

Oral enzyme supplements have been effectively used in individuals who:

  • Have occasional indigestion, diarrhea or constipation2
  • Have occasional low gastric acid due to aging2-4
  • Require enhanced B-12 absorption


The small intestine participates in all aspects of digestion, absorption, and transport of ingested materials. It secretes a variety of digestive and protective substances and receives the secretions of the pancreas, liver, and gallbladder.1

See also Hypo-Gest (double the strength). Priority One's Gastri-Gest offers a powerful combination of plant enzymes for vegetarian and vegan individuals.

Supplement Facts:

Serving Size: Two (2) Tablets
Servings Per Container: 125

Amount Per Serving / % DV

Stomach Ingredients:
Betaine HCI 220mg / **
L-Glutamic Acid 220mg / **
Pepsin (1:3‚000) 200mg / **
Papain (3‚000 USP/mg) 100mg / **
Intestine Ingredients:
Pancreatin (8X) 200mg / **
Amylase 40‚000 USP / **
Lipase 9‚000 USP / **
Protease 40‚000 USP / **
Pancrelipase 100mg / **
Amylase (5‚000 SKB/g) 60mg / **
Bromelain (1‚800 MCU/g) 80mg / **
Ox Bile Extract 120mg / **

**US Daily Value not established.

Other Ingredients:

Di-calcium phosphate‚ stearic acid (vegetable)‚ magnesium stearate (vegetable)‚ microcrystalline cellulose‚ silicon dioxide‚ croscarmellose sodium‚ gluten-free maltodextrin‚ natural modified cellulose.

Contains Milk (from Pepsin).

Contains no preservatives.
Bisphenol-A (BPA) & Phthalate Free.

GMP Certified.


Adults two (2) tablets before meals as a dietary supplement or as directed by your physician (may also be taken after meals).


If you are pregnant or breastfeeding, consult your physician before using this product.

Keep the container tightly closed.
Store at a cool, dry temperature.
Keep out of reach of children.