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Professional Supplements & Nutritional Products Since 1998
What is CRPS | New Treatments for CRPS

What is CRPS | New Treatments for CRPS

What is CRPS? CRPS stands for Complex Regional Pain Syndrome. Dr. Smith’s CRPS protocol has worked on every CRPS patient he has treated. The reason mainstream approaches have not worked because they failed to address the root cause which is lymphedema. Learn more about CRPS treatment guidelines and CRPS symptoms in this discussion.

What is CRPS: Here's What You Need to Understand about the New Treatments for CRPS

In this Article:

CRPS Treatment Protocol

To understand what is CRPS, you must know about the CRPS treatment protocol. There are two key factors in the successful treatment of CRPS. The first is absolutely essential and that is to relieve the lymphatic congestion. The second is to restore glutathione levels, which is best done by addressing methylation issues. But first, the lymphatic congestion must be addressed first. If detoxification is attempted and the lymphatic congestion is not relieved, the condition will get worse.

3 CRPS Treatment Protocols:

  1. Improve Lymphatic Congestion
  2. Reduce sources of inflammation
  3. Increase glutathione levels

Supplements Used for Improvement of Lymphatic Flow

1. Proteolytic Enzymes  Enzyme Defense Pro: Start with 1 capsule 3 times per day with water and increase dosing gradually to 2 to 3 capsules per dose. Must be taken at least 30 minutes before a meal or at least one hour after.

2. Homeopathics: Hevert Detox Kit or Detox Lymph: Starting with the Fatigue bottle or Lymph Stim, use one drop in a glass of water two to three times per day. As long as there are no side effects, keep increasing the dosage to get up to about 10 to 15 drops of dose. Typically, if you are going to see side effects, it will be with the lower doses. If you are getting side effects such as increased itchiness or fatigue, then you just need to lower the dose.

Reducing GI Inflammation

Knowing what is CRPS involves knowing how to reduce GI inflammation. There is generally some G.I. inflammation in most chronically ill patients. A more definitive approach is included in our biofilm protocol. However, many patients may not have a severe biofilm, so these steps are designed to reduce bowel inflammation in most patients, but the approach may need to be modified.

  1. Biocidin– 1 to 2 capsules 2 to 3 times per day with food. This supplement reduces the excess bacterial load.
  2. CoreBiotic– 2 capsules once daily 30 minutes before eating. This probiotic represents the latest in probiotic research.  It combines 3 strains of soil-based probiotics.  Each strain has been thoroughly tested and sequenced.  The result is a more effective probiotic and an improved immune system

Vitamin D

I have not found a single vitamin D deficient person who was not supplementing with vitamin D. Our goal is a serum level between 60 and 80 ng/dl. It will typically take a dose of between 5,000 and 10,000 units of vitamin D per day to achieve this level. Most of the benefits of vitamin D do not start until the serum levels exceed 50 ng/dL. I have found the easiest and most affordable way to take vitamin D is to use high-dose vitamin D capsules. I with 50,000 units per day for the first week and then drop back to 1 to 2 capsules per week for maintenance depending on body size.

Vitamin D 50,000 units: 1 daily for one week, then 1 per week for women and 2 per week for men.

Goal level: Serum level 60 to 80 ng/dl.
Note: Do not take extra calcium when taking this level of vitamin D.



There are many choices of antioxidants and anti-inflammatory compounds. My favorite is Soul by Rain international. This is an MLM product. It has many advantages over other products I’ve tried. It is a juice made from the seeds of black cumin, black raspberry, and chardonnay grapes along with D-ribose sugar used by our bodies to make ATP.

Being a liquid, it is easily absorbed and tastes pretty good. You can apply it directly to the skin since it has good effects on the skin as well. This is particularly advantageous with CRPS. This product is inexpensive at the recommended dose of two per day. Soul cost $65 per box of 30 packets.

Tip: Curcumin is also very effective, but poorly absorbed unless specially treated. Theracumin or Meriva are two compounds that have improved absorption. The dose of curcumin is 300 mg to 600 mg twice daily.

Mitochondrial Support

Mitochondrial Support is also crucial in learning what is CRPS. Mitochondria produce energy for our body. Chronic stress can impair mitochondrial function. Cells can contain several thousand mitochondria and their proper function is essential for healing. We have tested numerous products that claim to provide mitochondrial support. Most of the products we tested did not work.

However, we found one product that was well-researched and works well clinically. We have also found a few others that do have some activity. Yet, ATP Fuel has been, by far, the most effective product we have found. We use this product exclusively unless there is some allergic reaction to the product, in which case, we have to switch to something else. Typically, we see a fairly rapid response to ATP Fuel. Most people see an improvement in their energy and well-being within the first week.

Mitochondrial support: ATP Fuel Dose: 5 capsules twice daily on empty stomach for the first month and then 5 capsules per day for maintenance.

Reduce Galectin – 3

Galectin -3 is associated with numerous chronic illnesses including heart disease and cancer. PectaSol-3 binds Galectin-3 and other toxins. We find it very useful in any patient with chronic toxicity. The other advantage of PectaSol-C is there are rarely any side effects from the supplement. PectaSol-C is a fiber product and can cause loose stools in excess.

PectaSol-C Dosing: 6 capsules daily on an empty stomach. You may increase the dose to three times a day if needed.

Methylation Support

Most people with CRPS have methylation issues. We use Agape Methyl B12 and Folate to provide active forms of folate and B12.

Note: HydroxyB12 supports the production of active B12 (methyl B12)
Dose: 1 tablet per day

Perque Activated B12 Guard: Dose is 1 tablet SL per day 

To know more about what is CRPS, check out this video from the ABC Action News channel:


May this article about CRPS' new treatments and CRPS supplements shed some light on those who are suffering from this condition. Don't forget to reach out to us, Agape Nutrition, if you have queries and concerns. 

Do you have insights you want to share about what is CRPS? Tell us in the comments section below!

Up Next: Biofilm Protocol Explained

Product Links:


Hevert Detox Kit
Hevert Detox Lymph

*This article was originally published in 2016