Ecological Formulas | Pteridin-4 | 60 Capsules

Pteridin-4 | 60 Capsules:

Homeopathic Supplement

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Pteridin-4 contains biopterin, a cofactor to citical enzyme pathways in human physiology.

 

Tetrahydrobiopterin Deficiency is a rare genetic, neurological disorder present at birth. It is caused by an inherited inborn error of metabolism. Tetrahydrobiopterin is a natural substance (coenzyme) that enhances the action of other enzymes. When Tetrahydrobiopterin is deficient, an abnormally high blood level of the amino acid phenylalanine, along with low levels of certain neurotransmitters, usually occurs. To avoid irreversible neurological damage, diagnosis and treatment of this progressive disorder is essential as early as possible in life.

 

The subdivisions of Tetrahydrobiopterin Deficiency are as follows:

  • Tetrahydrobiopterin Synthesis
  • GTP Cyclohydrolase I (GTPCH) Deficiency
  • 6-Pyruvoyl Tetrahydropterin Synthase (PTPS) Deficiency
  • Tetrahydrobiopterin Regeneration
  • Pterin-4-alpha-Carbinolamine Dehydratase (PCD) Deficiency
  • Dihydropteridine Reductase (DHPR) Deficiency 

Ingredients:

Vitamin C (as ascorbic acid) 10 mg, Tetrahydrobiopterin (a stable form of the physiologic agent, biopterin) 2.5 mg.

Other ingredients:

Sucrose, Gelatin, L-Leucine.

Directions:

Take one or two capsules daily or as directed by a physician.

Bottle Contains: 60 Capsules

 

Storage:

Refrigerate and keep tightly closed to maintain product potency and to maximize shelf life.

 

History:

Tetrahydrobiopterin was discovered to play a role as an enzymatic cofactor. The first enzyme found to use tetrahydrobiopterin is phenylalanine hydroxylase (PAH).

 

Biosynthesis:

Tetrahydrobiopterin is biosynthesized from guanosine triphosphate (GTP) by three chemical reactions mediated by the enzymes GTP cyclohydrolase I (GTPCH), 6-pyruvoyltetrahydropterin synthase (PTPS), and sepiapterin reductase (SR).

 

Functions:

Tetrahydrobiopterin has the following responsibilities as a cofactor:

  • Tryptophan hydroxylase (TPH) for the conversion of L-tryptophan (TRP) to 5-hydroxytryptophan (5-HTP)
  • Phenylalanine hydroxylase (PAH) for conversion of L-phenylalanine (PHE) to L-tyrosine (TYR)
  • Tyrosine hydroxylase (TH) for the conversion of L-tyrosine to L-DOPA (DOPA)
  • Nitric oxide synthase (NOS) for conversion of a guanidino nitrogen of L-arginine (L-Arg) to nitric oxide (NO)
  • Alkylglycerol monooxygenase (AGMO) for the conversion of 1-alkyl-sn-glycerol to 1-hydroxyalkyl-sn-glycerol

Some information was sourced. Please visit: WebMDfor additional information and resources.

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